A Database for Oncogenic & Tumor-Suppressive MicroRNAs

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MicroRNAs (miRNAs), a class of endogenous small regulatory RNAs, play important roles in many biological and physiological processes. Till now, many miRNAs are shown to be functionally related to cancer initiation, development and therapy. To facilitate the study on cancer-related miRNAs, we set up this oncomiRDB database aiming at annotating the experimentally verified oncogenic and tumor-suppressive miRNAs from literature. This database only collects items having direct functional evidences: 1) the miRNA regulates at least one cancer-related phenotype or cellular process (such as proliferation, apoptosis, migration and invasion, senescence and cell cycle regulation); or 2) the miRNA directly regulates at least one oncogenic or tumor-suppressive gene verified by luciferase reporter assay. It should be a very useful resource for both the computational analysis and the experimental study on miRNA regulations in cancer.

Citation: Dongfang Wang, Jin Gu#, Ting Wang, Zijian Ding. OncomiRDB: a database for the experimentally verified oncogenic and tumor-suppressive microRNAs. Bioinformatics 2014, 30(15):2237-2238.

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Cancer-MicroRNA Network


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Latest Statistics:


Latest Update: Jan 06, 2014
Number of entries:  2259
Number of miRNAs:  328
Number of targets:  829

Statistical Chart:


Most Annotated MicroRNAs

RankMiRNANumber
1miR-21-5p119
2miR-34a-5p74
3miR-145-5p63
4miR-200c-3p53
5let-7a-5p47


Most Annotated Tissues

RankTissueNumber
1breast142
2liver130
3colorectum105
4lung96
5stomach90